Plasma cell gingivitis pcg is a rare inflammatory disease of the gums, which is defined by plasma cell infiltration into subepithelial tissue. Plasmoacanthoma and plasma cell cheilitis are rare disorders of obscure etiology characterized by a plasma cell infiltrate. Plasma cell gingivitis related to the use of herbal. Generalized aggressive periodontitis associated with a. Plasma cell gingivitis is a rare benign condition of the gingiva characterized by sharply demarcated erythematous and edematous gingivitis often extending to the mucogingival junction. Plasma cell gingivitis with aggressive periodontitis.
Plasma cell gingivitis an unusual case of simultaneus. The diagnostic workup includes comprehensive history taking, examination and laboratory tests to rule. The lesion was believed to have been largely eliminated by removing the allergens from the products. The etiology is largely unknown, and it is thought to be due to a hypersensitivity reaction to an allergen. The lamina propria revealed extremely dense infiltration of chronic inflammatory cell infiltrate that was composed predominantly of plasma cells, few russel bodies and numerous dilated vascular channels were consistently seen throughout the stroma tablefig4,5. Plasma cell gingivitis, which is also called atypical gingivitis or plasma cell gingivostomatitis, is a rare benign inflammatory condition of unknown aetiology. The histologic appearance was compatible with plasma cell gingivitis. Diagnosis of plasma cell gingivitis from a dental referral of. Hypersensitivity reaction due to antigen is considered as primary etiological factor.
The importance of this lesion is that it may cause severe gingival inflammation, discomfort, and. Plasma cell gingivitis pcg is a rare condition characterized by diffuse and massive infiltration of plasma cells into the subepithelial gingival tissue. Plasma cell gingivitis is an infrequent benign inflammatory condition of unknown etiology. Case report a rare case of plasma cell gingivitis with. Plasma cell gingivitis kandwal a et al 187 association of pcg and chelitis is very rare and proper involvement of periodontist and dermatologist is necessary to treat the condition. Cheilitis, gingivectomy, hypersensitivity, plasma cell gingivitis. As clinical findings in this patient, the peripheral region of the upper and lower gingivae was swollen and painful. Plasma cell gingivitis is an uncommon inflammatory condition of the gingiva, characterized by plasma cell infiltration in the gingiva. We present the case of a yearold girl who had pcg with an erythematous congestive plaque on the anterior maxillary gingiva for 4 years. Various synonyms of plasma cell gingivitis are atypical gingivostomatitis, idiopathic gingivostomatitis, allergic gingivostomatitis, and plasma cell gingivostomatitis 1.
Clinically it appears as a diffuse reddening and edematous swelling. Plasma cell gingivitis europe pmc article europe pmc. Pdf plasma cell gingivitis pcg, an infrequent benign inflammatory condition of unknown etiology, is a type of plasma cell orificial mucositis, which. The associated cheilitis has dramatically reduced after treatment of the gingival lesion. Plasma cell gingivitis mimicking granulomatous disease. It may clinically present as isolated nodule granuloma or involve the whole gingiva. A recent article by joshi and shukla 2015 reported a patient with plasma cell gingivitis after prolonged use of herbal toothpowder. Introduction plasma cell gingivitis is dense plasma cell infiltration in the gingiva secondary to hypersensitive reaction 1,2. Discontinuation of the offending products promoted an elimination of the gingivitis. It has a higher rate of reoccurrence and needs a detailed and careful analysis of etiology.
Plasma cell gingivitis pcg is a rare condition of the gingiva, characterized by in fi ltration of plasma cells. Plasma cell gingivitis is a rare benign condition of the gingiva characterised by sharply demarcated erythaematous and oedematous gingiva often extending up to the muco gingival junction. Plasma cell gingivitis is a rare condition, appearing as generalized erythema redness and. A rare case of plasma cell gingivitis with cheilitis hindawi. In most of the cases the underlying etiology is allergic reaction to a foreign substance such as cinnamon, chewing gum, spices or dentifrices. Pdf plasma cell gingivitis pcg is a rare condition of the gingiva, characterized by in fi ltration of plasma cells.
Pdf plasma cell gingivitis thomas sollecito academia. The present case is of an 18yearold male patient suffering from gingival enlargement along with cheilitis. Plasma cell gingivitis is a condition that often consists of a mild enlargement of the gums at the marginal areas which may extend to the gums attached over the alveolar bone. Plasma cell gingivitis pcg is a rare benign condition of the gingiva. The etiology is largely unknown, but it is thought to be due to a hypersensitivity. Sole involvement of the gingiva is not uncommon and is frequently misdiagnosed as inflammatory periodontal disease. Case report plasma cell gingivitis with severe alveolar. The diagnosis is based on comprehensive history taking, clinical examination and appropriate. Plasma cell gingivitis is a rare condition characterized by diffuse and massive infiltration of plasma cells into the subepithelial connective tissue. Clinical signs of gingivitis either do not appear as plaque accumulates, or they are greatly delayed in children, and the inflammatory infiltrate consists mostly of t lymphocytes. The etiologic agent must be identified and the substance eliminated from use. Plasma cell gingivitis may produce the swelling of the. Plaque control and conventional periodontal therapy alone will not cure this disease. These include rare cases of extramedullary plas macytoma, plasmacytosis of the gingiva,1 plasmacell gingivitis,2 and plasma cell granuloma.
Dentists are of the opinion that i have plasma cell gingivitis and need an operation, which i am not keen on. Gingivitis has been classified by clinical appearance eg, ulcerative, hemorrhagic, necrotizing, purulent, etiology eg, druginduced, hormonal, nutritional, infectious, plaqueinduced, and. A recent article by joshi and shukla 2015 reported a patient with plasma cell gingivitis. The conversion to a b cell lesion does not appear to occur. This benign condition is characterized by gingival erythema and edema. Plasma cell gingivitis pcg is a rare condition of the gingiva which is characterized by massive infiltration of plasma cells into the underlying subepithelial connective tissue.
Introduction plasma cell gingivitis is an uncommon benign inflammatory condition of the gingiva which is considered to arise as a hypersensitivity reaction to certain allergens. A rare case of plasma cell gingivitis with cheilitis. Full text pdf 3363k abstracts references11 we describe a case of plasma cell gingivitis that occurred in the upper and lower gingivae of a 38yearold man. Identified as an allergic reaction to a component of chewing gum, such as cinnamon or mint, it can also be caused by clove, or other herbal products in toothpaste, red peppers, chewing gum of khat leaves. Plasma cell gingivitis among herbal toothpaste users. Desquamative gingivitis an overview sciencedirect topics. Plasma cells are also associated with diseases such as plasma cell pododermatitis and plasma cell chondritis the lesions have a tendency to ulcerate and bleed. Plasma cell gingivitis pcg is a rare benign condition of the gingiva characterized by sharply demarcated erythematous and edematous gingivitis often extending to the mucogingival junction. It presents clinically as a diffuse, erythematous and edematous inflammation of the gingiva that extends to the mucogingival junction that bleeds frequently, with minimal trauma. Plasma cell gingivitis pgc is a rare disease of gingival tissues which is difficult to treat. Plasma cell gingivitis is a rare condition characterized by diffuse and massive infiltration of plasma cells into the subepithelial gingival tissue. Gingivitis and the periodontal microflora differ in children and adults. It manifests as extreme redness, swelling and gum tissue enlargement with propensity for bleeding, accompanied by extensive infiltration of plasma cells in the lamina propria.
Further, its association with chelitis is rare, only few cases have been reported and the condition with this presentation poses a diagnostic dilemma. Plasma cell gingivitis pcg is a rare condition of the gingiva, characterized by infiltration of plasma cells. Plasma cell gingivitis is a rare condition, appearing as generalized erythema redness and edema swelling of the attached gingiva, occasionally accompanied by cheilitis lip swelling or glossitis tongue swelling. Plasma cell gingivitis associated with inflammatory. Plasma cell gingivitis pcg, an infrequent benign inflammatory condition of unknown etiology, is a type of plasma cell orificial mucositis, which includes a wide spectrum of conditions. Introduction plasma cell gingivitis which is also called atypical gingivitis or plasma cell gingivostomatitis, is a rare benign inflammatory condition of unknown aetiology. The condition is also known as atypical gingivitis, plasma cell gingivostomatitis and plasma cell granuloma. Plasma cell stomatitis is characterised by painful proliferative lesions on the palatoglossal folds and arches. Gingivitis is an inflammatory process limited to the mucosal epithelial tissue surrounding the cervical portion of the teeth and the alveolar processes. Although the etiology may be unknown, this is believed to be a hypersensitivity reaction in some cases. Plasma cell gingivitis pcg is a rare condition of the gingiva, characterized histopathologically by infiltration of plasma cells in connective tissue.
Plasma cell gingivitis related to the use of herbal toothpaste. In cats, it causes anorexia, halitosis, excessive salivation and weight loss, often with associated gingivitis and stomatitis. Clinical differential diagnosis may include any of the desquamative gingivitis, such as erythematouserosive lichen planus, autoimmune. Non specific conditioned enlargement pyogenic granuloma tumor like gingival enlargement. Plasma cell gingivitis with severe alveolar bone loss. Histopathology plasma cell gingivitis epithelium spongiosis and infiltrated with chronic inflammatory cells. It is difficult to diagnose your condition without examining you, but if you have any underlining periodontal disease, then the disease should be treated appropriately. Clinically, it appears as gingival enlargement with erythema and swelling of the attached and free gingiva and is not associated with any loss of attachment. Plasma cell gingivitis which affects the gingiva, the palatal mucosa and the laryngeal cords. Unusual cases of plasma cell gingivitis periodontist. As the name suggests it is diffuse and massive infiltration of plasma cells into the subepithelial gingival tissue. The etiology is largely unknown, but it is thought to be.
Occasionally, the lesion became increasingly swollen and painful and. It is marked by a dense infiltrate of normal plasma cells separated into aggregates by strands of collagen. Also, some isolated generalized gingival lesions such as plasma cell gingivitis, plaque induced gingival hyperplasia, scurvy. It presents clinically as a diffuse, erythematous and papillary lesion of the gingiva, which frequently bleeds, with minimal trauma. Plasma cell gingivitis a case report and literature. It is called plasma cell gingivitis where the gingiva gums are involved, plasma cell cheilitis, where the lips are involved, and other terms such as plasma cell orifacial. Plasma cell gingivitis is a rare benign condition which presents as an enlargement of the gingiva, characterised by dense infiltration of plasma cells in the subepithelial connective tissue. Plasma cell gingivitis is a rare benign condition typified by nonneoplastic infiltrate of plasma cell into the gingival connective tissue. Plasma cell gingivitis is considered to be a rare condition of gingiva and represents a hypersensitive reaction with predominant plasma cell. Desquamative gingivitis is a fairly common disorder, with a wide range of causes, most commonly lichen planus and mucous membrane pemphigoid. An 80yearold woman presented with a verrucous, fleshy, skin colored plaque over lips, gingiva, and the palate and painful swallowing for over a period of 6 months. Fulltext pdf histopathological analysis of unilateral condylar hyperplasia. Plasma cell gingivitis pcg is an unusual inflammatory condition characterized by dense, band. Plasma cell gingivitis is a disorder first described in the 1960s and was believed to be caused by an allergic reaction to flavored chewing gum and toothpaste.
Plasma cell gingivitis pcg, an infrequent benign inflammatory condition of unknown etiology, is a type of plasma cell orificial mucositis, which includes a wide. Plasma cell gingivitis joshi c, shukla p j indian soc. The clinical diagnosis was gingival hypertrophy, and primary. Its etiology is unknown, but hypersensitivity reaction has been proposed. This report outlines a case of plasma cell gingivitis which may have been brought on by the use of red peppers in. Plasma cell infiltration is also found in other organs of the system like the lung, bronchi, liver, kidney, spinal cord, intracranial space, thyroid gland and stomach. Plasma cell gingivitis pcg is a rare condition of gingiva marked by diffuse plasma cells into the subepithelial gingival tissue. Plasma cell gingivitis is an uncommon condition, characterised by a sharply demarcated, erythematous and oedematous gingivitis, often extending to the mucogingival junction. Plasma cell gingivitis pcg is a relatively rare disease that usually occurs on the anterior maxillary and mandibular gingiva. It presents clinically as a diffuse, erythaematous and papillary lesion of the gingiva, which frequently bleeds, with minimal trauma. Plasma cell gingivitis associated with dry flower buds of clove.